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Year
Title
Publication
Lead Author
2024
Idiopathic multicentric Castleman disease with marrow fibrosis and extramedullary hematopoiesis
2024 | Bloomers
Idiopathic multicentric Castleman disease with marrow fibrosis and extramedullary hematopoiesis
2023
Immune-mediated thrombocytopenia and IL- 6-mediatedthrombocytosis observed in idiopathic multicentric Castleman disease
2023 | Rubenstein
Immune-mediated thrombocytopenia and IL- 6-mediatedthrombocytosis observed in idiopathic multicentric Castleman disease
2023
Refractory idiopathic multicentric Castleman disease responsive to sirolimus therapy
2023 | Bayram
Refractory idiopathic multicentric Castleman disease responsive to sirolimus therapy
2023
Treatment consistent with idiopathic multicentric Castleman disease guidelines is associated with improved outcomes clinical trials & observations
2023 | Pierson
Treatment consistent with idiopathic multicentric Castleman disease guidelines is associated with improved outcomes clinical trials & observations
2023
A model for crowdsourcing high-impact research questions for Castleman disease and other rare diseases
2023 | Korsunska
A model for crowdsourcing high-impact research questions for Castleman disease and other rare diseases
2023
A national, multicenter, retrospective study of Castleman disease in China implementing CDCN criteria
2023 | Zhang
A national, multicenter, retrospective study of Castleman disease in China implementing CDCN criteria
2023
Ongoing symptoms following complete surgical excision in unicentric Castleman disease
2023 | Sarmiento Bustamante
Ongoing symptoms following complete surgical excision in unicentric Castleman disease
2023
Siltuximab administration results in spurious IL-6 elevation in peripheral blood
2023 | Mango
Siltuximab administration results in spurious IL-6 elevation in peripheral blood
2023
Longitudinal, natural history study reveals the disease burden of idiopathic multicentric Castleman disease
2023 | Sarmiento Bustamante
Longitudinal, natural history study reveals the disease burden of idiopathic multicentric Castleman disease
2022
How we manage idiopathic multicentric Castleman disease
2022 | Brandstadter
How we manage idiopathic multicentric Castleman disease
2022
Epidemiology and treatment patterns of idiopathic multicentric Castleman disease in the era of IL-6–directed therapy
2022 | Mukherjee
Epidemiology and treatment patterns of idiopathic multicentric Castleman disease in the era of IL-6–directed therapy
2022
P1140: Time to tumor, symptomatic and laboratory responses following siltuximab treatment in idiopathic multicentric Castleman disease
2022 | Van Rhee
P1140: Time to tumor, symptomatic and laboratory responses following siltuximab treatment in idiopathic multicentric Castleman disease
2022
A prospective, multicenter study of bortezomib, cyclophosphamide and dexamethasone in relapsed/refractory iMCD
2022 | Zhang
A prospective, multicenter study of bortezomib, cyclophosphamide and dexamethasone in relapsed/refractory iMCD
2022
Siltuximab is associated with improved progression-free survival in idiopathic multicentric Castleman disease
2022 | Van Rhee
Siltuximab is associated with improved progression-free survival in idiopathic multicentric Castleman disease
2022
Optimisation of anti-interleukin-6 therapy: Precision medicine through mathematical modelling
2022 | Rossi
Optimisation of anti-interleukin-6 therapy: Precision medicine through mathematical modelling
2022
Global public awareness of Castleman disease and TAFRO syndrome between 2015 and 2021: A Google Trends analysis
2022 | Nishimura
Global public awareness of Castleman disease and TAFRO syndrome between 2015 and 2021: A Google Trends analysis
2022
Organ dysfunction, thrombotic events and malignancies in patients with idiopathic multicentric castleman disease: a population-level US health claims analysis
2022 | Mukherjee
Organ dysfunction, thrombotic events and malignancies in patients with idiopathic multicentric castleman disease: a population-level US health claims analysis
2022
Idiopathic Multicentric Castleman Disease Occurring Shortly after mRNA SARS-CoV-2 Vaccine
2022 | Hoffman
Idiopathic Multicentric Castleman Disease Occurring Shortly after mRNA SARS-CoV-2 Vaccine
2022
Adrenalitis and anasarca in idiopathic multicentric Castleman Disease
2022 | Chen
Adrenalitis and anasarca in idiopathic multicentric Castleman Disease
2022
Idiopathic multicentric Castleman disease with arteriolar endotheliopathy and secondary hemophagocytosis
2022 | Campbell
Idiopathic multicentric Castleman disease with arteriolar endotheliopathy and secondary hemophagocytosis
2022
Transcriptome and unique cytokine microenvironment of Castleman disease
2022 | Wing
Transcriptome and unique cytokine microenvironment of Castleman disease
2022
The disease course of Castleman disease patients with fatal outcomes in the ACCELERATE registry
2022 | Fajgenbaum
The disease course of Castleman disease patients with fatal outcomes in the ACCELERATE registry
2022
Bone marrow findings of idiopathic Multicentric Castleman disease: A histopathologic analysis and systematic literature review
2022 | Belyaeva
Bone marrow findings of idiopathic Multicentric Castleman disease: A histopathologic analysis and systematic literature review
2022
P1733: Non-Hematological Malignancies in Idiopathic Multicentric Castleman Disease Patients: A Matched Cohort Analysis Using a Health Claims-Based Dataset
2022 | Mukherjee
P1733: Non-Hematological Malignancies in Idiopathic Multicentric Castleman Disease Patients: A Matched Cohort Analysis Using a Health Claims-Based Dataset
2022
Thrombocytopenia, anasarca, and severe inflammation
2022 | Montazeripouragha
Thrombocytopenia, anasarca, and severe inflammation
2022
CXCL13 is a predictive biomarker in idiopathic multicentric Castleman disease
2022 | Pierson
CXCL13 is a predictive biomarker in idiopathic multicentric Castleman disease
2022
Increased mTORC2 pathway activation in lymph nodes of iMCD-TAFRO
2022 | Phillips
Increased mTORC2 pathway activation in lymph nodes of iMCD-TAFRO
2022
The lymph node transcriptome of unicentric and idiopathic multicentric Castleman disease
2022 | Horna
The lymph node transcriptome of unicentric and idiopathic multicentric Castleman disease
2021
UCD with MCD-like inflammatory state: surgical excision is highly effective
2021 | Zhang
UCD with MCD-like inflammatory state: surgical excision is highly effective
2021
TAFRO Syndrome and Elusive Diagnosis of Idiopathic Multicentric Castleman Disease Treated with Empiric Anti-Interleukin-6 Therapy
2021 | Williams
TAFRO Syndrome and Elusive Diagnosis of Idiopathic Multicentric Castleman Disease Treated with Empiric Anti-Interleukin-6 Therapy
2021
Association between Insufficient Interleukin-6 (IL-6) Inhibition and Worsening Outcomes in COVID-19 and Idiopathic Multicentric Castleman Disease (iMCD), and a Mathematical Model to Predict Optimal Dosing to Completely Block IL-6 Activity
2021 | Rossi
Association between Insufficient Interleukin-6 (IL-6) Inhibition and Worsening Outcomes in COVID-19 and Idiopathic Multicentric Castleman Disease (iMCD), and a Mathematical Model to Predict Optimal Dosing to Completely Block IL-6 Activity
2021
Discovery and validation of a novel subgroup and therapeutic target in idiopathic multicentric Castleman disease
2021 | Pierson
Discovery and validation of a novel subgroup and therapeutic target in idiopathic multicentric Castleman disease
2021
Castleman disease
2021 | Carbone
Castleman disease
2021
Safety and Tolerability of Sars-Cov-2 Vaccination and Natural History of Infection Among Patients with Castleman Disease
2021 | Pierson
Safety and Tolerability of Sars-Cov-2 Vaccination and Natural History of Infection Among Patients with Castleman Disease
2021
Validated international definition of the thrombocytopenia, anasarca, fever, reticulin fibrosis, renal insufficiency, and organomegaly clinical subtype (TAFRO) of idiopathic multicentric Castleman disease
2021 | Nishimura
Validated international definition of the thrombocytopenia, anasarca, fever, reticulin fibrosis, renal insufficiency, and organomegaly clinical subtype (TAFRO) of idiopathic multicentric Castleman disease
2021
Emerging role of 18F-FDG PET/CT in Castleman disease: a review
2021 | Koa
Emerging role of 18F-FDG PET/CT in Castleman disease: a review
2021
Novel somatic alterations in unicentric and idiopathic multicentric Castleman disease
2021 | Goodman
Novel somatic alterations in unicentric and idiopathic multicentric Castleman disease
2020
Insufficient evidence exists to use histopathologic subtype to guide treatment of idiopathic multicentric Castleman disease
2020 | Fajgenbaum
Insufficient evidence exists to use histopathologic subtype to guide treatment of idiopathic multicentric Castleman disease
2020
ACCELERATE: A Patient-Powered Natural History Study Design Enabling Clinical and Therapeutic Discoveries in a Rare Disorder
2020 | Pierson
ACCELERATE: A Patient-Powered Natural History Study Design Enabling Clinical and Therapeutic Discoveries in a Rare Disorder
2020
Cytokine Storm
2020 | Fajgenbaum
Cytokine Storm
2020
AA amyloidosis associated with Castleman disease
2020 | Bernabei
AA amyloidosis associated with Castleman disease
2020
Genetic basis for iMCD-TAFRO
2020 | Yoshimi
Genetic basis for iMCD-TAFRO
2020
Type I IFN response associated with mTOR activation in the TAFRO subtype of idiopathic multicentric Castleman disease
2020 | Langan Pai
Type I IFN response associated with mTOR activation in the TAFRO subtype of idiopathic multicentric Castleman disease
2020
Increased mTOR activation in idiopathic multicentric Castleman disease
2020 | Arenas
Increased mTOR activation in idiopathic multicentric Castleman disease
2020
Overview of Castleman disease
2020 | Dispenzieri
Overview of Castleman disease
2020
International evidence-based consensus diagnostic and treatment guidelines for unicentric Castleman disease
2020 | Van Rhee
International evidence-based consensus diagnostic and treatment guidelines for unicentric Castleman disease
2019
Renal Pathologic Findings in TAFRO Syndrome: Is There a Continuum Between Thrombotic Microangiopathy and Membranoproliferative Glomerulonephritis? A Case Report and Literature Review
2019 | Leurs
Renal Pathologic Findings in TAFRO Syndrome: Is There a Continuum Between Thrombotic Microangiopathy and Membranoproliferative Glomerulonephritis? A Case Report and Literature Review
2019
Virome capture sequencing does not identify active viral infection in unicentric and idiopathic multicentric Castleman disease
2019 | Nabel
Virome capture sequencing does not identify active viral infection in unicentric and idiopathic multicentric Castleman disease
2019
Identifying and targeting pathogenic PI3K/AKT/mTOR signaling in IL-6 blockade–refractory idiopathic multicentric Castleman disease
2019 | Fajgenbaum
Identifying and targeting pathogenic PI3K/AKT/mTOR signaling in IL-6 blockade–refractory idiopathic multicentric Castleman disease
2018
Predictors of response to anti-IL6 monoclonal antibody therapy (siltuximab) in idiopathic multicentric Castleman disease: secondary analyses of phase II clinical trial data
2018 | Morra
Predictors of response to anti-IL6 monoclonal antibody therapy (siltuximab) in idiopathic multicentric Castleman disease: secondary analyses of phase II clinical trial data
2018
Effectiveness of Rituximab-Containing Treatment Regimens in Idiopathic Multicentric Castleman Disease
2018 | Dong
Effectiveness of Rituximab-Containing Treatment Regimens in Idiopathic Multicentric Castleman Disease
2018
Schnitzler syndrome co-occurring with idiopathic multicentric Castleman disease that responds to anti-IL-1 therapy: A case report and clue to pathophysiology
2018 | Soudet
Schnitzler syndrome co-occurring with idiopathic multicentric Castleman disease that responds to anti-IL-1 therapy: A case report and clue to pathophysiology
2018
The full spectrum of Castleman disease: 273 patients studied over 20 years
2018 | Oksenhendler
The full spectrum of Castleman disease: 273 patients studied over 20 years
2018
Novel insights and therapeutic approaches in idiopathic multicentric Castleman disease
2018 | Fajgenbaum
Novel insights and therapeutic approaches in idiopathic multicentric Castleman disease
2018
Next-generation sequencing of idiopathic multicentric and unicentric Castleman disease and follicular dendritic cell sarcomas
2018 | Nagy
Next-generation sequencing of idiopathic multicentric and unicentric Castleman disease and follicular dendritic cell sarcomas
2018
A novel FAS mutation with variable expressivity in a family with unicentric and idiopathic multicentric Castleman disease
2018 | Baker
A novel FAS mutation with variable expressivity in a family with unicentric and idiopathic multicentric Castleman disease
2018
Plasma proteomics identifies a ‘chemokine storm’ in idiopathic multicentric Castleman disease
2018 | Pierson
Plasma proteomics identifies a ‘chemokine storm’ in idiopathic multicentric Castleman disease
2018
International, evidence-based consensus treatment guidelines for idiopathic multicentric Castleman disease
2018 | Van Rhee
International, evidence-based consensus treatment guidelines for idiopathic multicentric Castleman disease
2017
Preliminary Results from Accelerate, an International, Web-Based, Natural History Registry of Castleman Disease
2017 | Fajgenbaum
Preliminary Results from Accelerate, an International, Web-Based, Natural History Registry of Castleman Disease
2017
Leveraging information and collaboration to cure disease
2017 | Fajgenbaum
Leveraging information and collaboration to cure disease
2017
Virome Capture Sequencing in Castleman Disease Identifies Associations with Herpesviridae Family Members but No Novel Viruses
2017 | Nabel
Virome Capture Sequencing in Castleman Disease Identifies Associations with Herpesviridae Family Members but No Novel Viruses
2017
Prolonged Remission Achieved in a Relapsing Idiopathic Multicentric Castleman Disease Patient with a Novel, Targeted Treatment Approach
2017 | Fajgenbaum
Prolonged Remission Achieved in a Relapsing Idiopathic Multicentric Castleman Disease Patient with a Novel, Targeted Treatment Approach
2017
TAFRO syndrome: New subtype of idiopathic multicentric Castleman disease
2017 | Srkalovic
TAFRO syndrome: New subtype of idiopathic multicentric Castleman disease
2017
TAFRO Syndrome in Caucasians: A Case Report and Review of the Literature
2017 | Louis
TAFRO Syndrome in Caucasians: A Case Report and Review of the Literature
2017
Clinical and pathological characteristics of HIV- and HHV-8–negative Castleman disease
2017 | Yu
Clinical and pathological characteristics of HIV- and HHV-8–negative Castleman disease
2017
Quantification of Plasma Proteins from Idiopathic Multicentric Castleman Disease Flares and Remissions Reveals ‘Chemokine Storm’ and Separates Clinical Subtypes
2017 | Pierson
Quantification of Plasma Proteins from Idiopathic Multicentric Castleman Disease Flares and Remissions Reveals ‘Chemokine Storm’ and Separates Clinical Subtypes
2017
Castleman Disease Pathogenesis
2017 | Fajgenbaum
Castleman Disease Pathogenesis
2017
International, evidence-based consensus diagnostic criteria for HHV-8–negative/idiopathic multicentric Castleman disease
2017 | Fajgenbaum
International, evidence-based consensus diagnostic criteria for HHV-8–negative/idiopathic multicentric Castleman disease
2016
The collaborative network approach: a new framework for accelerating Castleman’s disease and other rare disease research
2016 | Fajgenbaum
The collaborative network approach: a new framework for accelerating Castleman’s disease and other rare disease research
2016
Siltuximab: a targeted therapy for idiopathic multicentric Castleman disease
2016 | Fajgenbaum
Siltuximab: a targeted therapy for idiopathic multicentric Castleman disease
2016
Idiopathic multicentric Castleman’s disease: a systematic literature review
2016 | Liu
Idiopathic multicentric Castleman’s disease: a systematic literature review
2016
Clinical Characterization of Castleman’s Disease in A Group of Pediatric Patients
2016 | Burlakov
Clinical Characterization of Castleman’s Disease in A Group of Pediatric Patients
2016
Potential value of FDG PET-CT in diagnosis and follow-up of TAFRO syndrome
2016 | Behnia
Potential value of FDG PET-CT in diagnosis and follow-up of TAFRO syndrome
2016
Clinicopathologic analysis of TAFRO syndrome demonstrates a distinct subtype of HHV-8-negative multicentric Castleman disease
2016 | Iwaki
Clinicopathologic analysis of TAFRO syndrome demonstrates a distinct subtype of HHV-8-negative multicentric Castleman disease
2015
Treatment of Castleman Disease
2015 | Fajgenbaum
Treatment of Castleman Disease
2015
Taking Control of Castleman disease: Leveraging Precision Medicine Technologies to Accelerate Rare Disease Research
2015 | Newman
Taking Control of Castleman disease: Leveraging Precision Medicine Technologies to Accelerate Rare Disease Research
2015
Multicentric Castleman’s Disease in a Child Revealed by Chronic Diarrhea
2015 | Benmiloud
Multicentric Castleman’s Disease in a Child Revealed by Chronic Diarrhea
2015
Clinical and laboratory characterization of 114 cases of Castleman disease patients from a single centre: paraneoplastic pemphigus is an unfavourable prognostic factor
2015 | Dong
Clinical and laboratory characterization of 114 cases of Castleman disease patients from a single centre: paraneoplastic pemphigus is an unfavourable prognostic factor
2014
Sustained remission of severe Multicentric Castleman disease following multiagent chemotherapy and tocilizumab maintenance
2014 | Turcotte
Sustained remission of severe Multicentric Castleman disease following multiagent chemotherapy and tocilizumab maintenance
2014
Siltuximab: first global approval
2014 | Markham
Siltuximab: first global approval
2014
Siltuximab for multicentric Castleman’s disease: a randomised, double-blind, placebo-controlled trial
2014 | Van Rhee
Siltuximab for multicentric Castleman’s disease: a randomised, double-blind, placebo-controlled trial
2014
HHV-8-Negative, Idiopathic Multicentric Castleman Disease (iMCD): A Description of Clinical Features and Therapeutic Options through a Systematic Literature Review
2014 | Fajgenbaum
HHV-8-Negative, Idiopathic Multicentric Castleman Disease (iMCD): A Description of Clinical Features and Therapeutic Options through a Systematic Literature Review
2014
Clinical and Experimental Study of Castleman Disease in Children
2014 | Zhang
Clinical and Experimental Study of Castleman Disease in Children
2014
Monoclonality and cytogenetic abnormalities in hyaline vascular Castleman disease
2014 | Chang
Monoclonality and cytogenetic abnormalities in hyaline vascular Castleman disease
2014
HHV-8-negative, idiopathic multicentric Castleman disease: novel insights into biology, pathogenesis, and therapy
2014 | Fajgenbaum
HHV-8-negative, idiopathic multicentric Castleman disease: novel insights into biology, pathogenesis, and therapy
2013
A phase I, open-label study of siltuximab, an anti-IL-6 monoclonal antibody, in patients with B-cell non-Hodgkin lymphoma, multiple myeloma, or Castleman disease
2013 | Kurzock
A phase I, open-label study of siltuximab, an anti-IL-6 monoclonal antibody, in patients with B-cell non-Hodgkin lymphoma, multiple myeloma, or Castleman disease
2013
Eruptive Cherry Hemangiomatosis Associated With Multicentric Castleman Disease
2013 | Fajgenbaum
Eruptive Cherry Hemangiomatosis Associated With Multicentric Castleman Disease
2013
Interleukin-6 Receptor Polymorphism Is Prevalent in HIV-negative Castleman Disease and Is Associated with Increased Soluble Interleukin-6 Receptor Levels
2013 | Stone
Interleukin-6 Receptor Polymorphism Is Prevalent in HIV-negative Castleman Disease and Is Associated with Increased Soluble Interleukin-6 Receptor Levels
2012
Surgery in Castleman’s disease: a systematic review of 404 published cases
2012 | Talat
Surgery in Castleman’s disease: a systematic review of 404 published cases
2012
Recent advances in Kaposi sarcoma herpesvirus-associated multicentric Castleman disease
2012 | Uldrick
Recent advances in Kaposi sarcoma herpesvirus-associated multicentric Castleman disease
2010
Castleman disease in the 21st century: an update on diagnosis, assessment, and therapy
2010 | Van Rhee
Castleman disease in the 21st century: an update on diagnosis, assessment, and therapy
2010
Successful treatment of Castleman’s disease with interleukin-1 receptor antagonist (Anakinra)
2010 | El-Osta
Successful treatment of Castleman’s disease with interleukin-1 receptor antagonist (Anakinra)
2007
Anti-interleukin-6 receptor antibody (tocilizumab) treatment of multicentric Castleman’s disease
2007 | Matsuyama
Anti-interleukin-6 receptor antibody (tocilizumab) treatment of multicentric Castleman’s disease
2005
Humanized anti–interleukin-6 receptor antibody treatment of multicentric Castleman disease
2005 | Nishimoto
Humanized anti–interleukin-6 receptor antibody treatment of multicentric Castleman disease
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