06/02/2025 Important insight for Castleman disease patients: Castleman disease (CD) is a major diagnostic challenge for rheumatologists. In this article the authors review and describe the wide range of symptoms exhibited by Castleman’s Disease (CD) patients and the overlap with other immune medicated conditions. The article reviews the different subtypes of CD, explaining the symptoms and the diagnostic criteria distinguishing each subtype. The treatment options for CD can be considered in three categories and are discussed. Patients with refractory disease have numerous treatment options and consulting treatment guidelines as well as consultation with a center with expertise in CD are recommended.
