Elaine S. Jaffe, MD is the Head of Hematopathology Section at the National Cancer Institute (NIH). Dr. Jaffe has conducted pioneering studies related to the classification of malignant lymphomas and has led an international effort for consensus among clinicians and pathologists. Her work focuses on lymphomas as tumors of the immune system.
Using a combination of immunophenotypic, genomic and genetic approaches, her group is examining the pathogenesis of lymphomas, mechanisms of transformation, and signaling pathways involved in control of cellular proliferation and differentiation. These studies delineate new disease entities and provide a basis for therapy. Her work has established a new paradigm for the classification of lymphoid neoplasms.